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Diagnosticul de mononucleoză infecţioasă se stabileşte pe date clinice (febră, faringită, adenopatii, hepatosplenomegalie), aspectul frotiului de sânge periferic (limfomonocite。

Anticorpi anti-antigenul precoce (Anti-EA, Early Antigen) Anticorpi anti-antigenul nuclear EBV (EBNA, EBV Nuclear Antigen) CDC nu mai recomanda folosirea in practica。

Descranticorpi heterofiliiere. Anticorpii heterofili sunt anticorpi umani indreptati impotriva antigenelor, prezenti la aproximativ 30% din populatie. Acesti anticorpi sunt produsi in situatiile detinerii animalelor de。

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